Compile Data Set for Download or QSAR
Found 7 of Enz. Inhib. data with enzyme = 'Stromelysin-1' and Substrate = 'MMP Fluorogenic Peptide Substrate'
TargetStromelysin-1(Homo sapiens (Human))
Istituto di Cristallografia

LigandPNGBDBM12075((2S)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...)copy SMILEScopy InChI
Affinity DataKi:  4.40nM ΔG°:  -11.4kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348HM7PubMed
TargetStromelysin-1(Homo sapiens (Human))
Istituto di Cristallografia

LigandPNGBDBM12072((R)-[1-(4-Methoxybiphenyl-4-sulfonylamino)-2-methy...)copy SMILEScopy InChI
Affinity DataKi:  40nM ΔG°:  -10.1kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348HM7PubMed
TargetStromelysin-1(Homo sapiens (Human))
Istituto di Cristallografia

LigandPNGBDBM12074((2R)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...)copy SMILEScopy InChI
Affinity DataKi:  54.9nM ΔG°:  -9.90kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348HM7PubMed
TargetStromelysin-1(Homo sapiens (Human))
Istituto di Cristallografia

LigandPNGBDBM8485((2R)-N-hydroxy-3-methyl-2-[(4-phenoxybenzene)sulfo...)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 6.0 T: 2°CAssay Description:Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348HM7PubMed
TargetStromelysin-1(Homo sapiens (Human))
Istituto di Cristallografia

LigandPNGBDBM12076((2R)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-N-h...)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 6.0 T: 2°CAssay Description:Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348HM7PubMed
TargetStromelysin-1(Homo sapiens (Human))
Istituto di Cristallografia

LigandPNGBDBM12077((2S)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-N-h...)copy SMILEScopy InChI
Affinity DataIC50: 810nMpH: 6.0 T: 2°CAssay Description:Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348HM7PubMed
TargetStromelysin-1(Homo sapiens (Human))
Istituto di Cristallografia

LigandPNGBDBM12073((S)-[1-(4-Methoxybiphenyl-4-sulfonylamino)-2-methy...)copy SMILEScopy InChI
Affinity DatapH: 7.5 T: 2°CAssay Description:Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348HM7PubMed